Search on: APC11 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor English:   Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   Subunidad Apc11 del Ciclosoma-Complejo Promotor de la Anafase 
Descriptor Portuguese:   Subunidade Apc11 do Ciclossomo-Complexo Promotor de Anáfase 
Tree Number:   D08.811.464.938.750.092.687
D12.776.167.024.687
Definition English:   Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55275 
Unique Identifier:   D064198 

Occurrence in VHL:
 

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